Keratosis Pilaris Is a Keratinization of Hair Follicles

Main Article Content

Chieh Chen
Da-ming Liao

Abstract

Keratosis pilaris is a common dermatological condition and is sometimes considered as a normal variant of the skin. It is also referred to as follicular keratosis. It is multifactorial and innocuous, affecting the extensor surfaces of the proximal extremities. Keratosis pilaris first appears in early childhood and progresses to become extensive during the second decade of life. Keratosis pilaris is also associated with many other conditions, including atopic dermatitis, ichthyosis vulgaris, obesity, diabetes mellitus, and malnutrition, as well as in conjunction with syndromes like Down syndrome and Noonan syndrome. Although the disease may improve over time, there are still some treatments available, including emollients, exfoliants, anti-inflammatory medication, phototherapy, and laser therapy.

Article Details

How to Cite
Chen, C. . and Liao, D.- ming (2023) “Keratosis Pilaris Is a Keratinization of Hair Follicles”, International Journal of Integrated Medical Research, 10(01), pp. 27–30. doi: 10.57181/ijoimr/vol10i01/105.
Section
Research Article

References

• Haber RN, Dib NG. Management of darier disease: A review of the literature and update. Indian Journal of Dermatology, Venereology and Leprology 2021; 87 (1): 14-21.

• Cohen L, Seminario-Vidal L, Lockey RF. Dermatologic problems commonly seen by the allergist/immunologist. J Allergy Clin Immunol Pract. 2020; 8 (1): 102-12.

• Thomas M, Khopkar US. Keratosis pilaris revisited: is it more than just a follicular keratosis? International Journal of Trichology 2012; 4 (4): 255.

• Castela E, Chiaverini C, Boralevi F, Hugues R, Lacour JP. Papular, profuse, and precocious keratosis pilaris. Pediatric Dermatology 2012; 29 (3): 285-8.

• Hosking AM, Elsensohn A, Makdisi J, Grando S, de Feraudy S. Keratosis pilaris rubra with mucin deposition. J Cutan Pathol. 2018; 45 (12): 958-61.

• Wang JF, Orlow SJ. Keratosis pilaris and its subtypes: associations, new molecular and pharmacologic etiologies, and therapeutic options. American journal of clinical dermatology 2018; 19 (5): 733-57.

• Sonthalia S, Bhatia J, Thomas M. Dermoscopy of keratosis pilaris. Indian Dermatology Online Journal 2019; 10 (5): 613-4.

• Reddy S, Brahmbhatt H. A narrative review on the role of acids, steroids, and kinase inhibitors in the treatment of keratosis pilaris. Cureus 2021; 13 (10).

• Hwang, S., Schwartz, RA. Keratosis pilaris: a common follicular hyperkeratosis. Cutis 2008; 82 (3): 177-180.

• Poskitt, L., Wilkinson, J. D. Natural history of keratosis pilaris. British Journal of Dermatology 1994; 130 (6), 711-713.

• Wat, H., Dytoc, M. Off-label uses of topical vitamin D in dermatology: a systematic review. Journal of cutaneous medicine and surgery 2014; 18 (2), 91-108.

• Gerbig, A. W. Treating keratosis pilaris. Journal of the American Academy of Dermatology 2002; 47 (3), 457.

• Lacarrubba, F., Nasca, M. R., Puglisi, D. F., Micali, G. Clinical evidences of urea at low concentration. International journal of clinical practice 2020; 74, e13626.

• Staubach, P., Baabaki, N., Yatskayer, M., Colón, G. 18078 Evaluation of the efficacy of an exfoliating cleanser and urea-containing cream on keratosis pilaris using clinical and 3D image-based analysis. Journal of the American Academy of Dermatology 2020; 83 (6), AB90.

• Pan, M., Heinecke, G., Bernardo, S., Tsui, C., Levitt, J. Urea: a comprehensive review of the clinical literature. Dermatology online journal 2013, 19 (11).

• Maghfour J, Ly S, Haidari W, Taylor SL, Feldman SR. Treatment of keratosis pilaris and its variants: a systematic review. Journal of Dermatological Treatment 2020: 1-12.