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Anthrax is an ancient disease which is per acute with the zoonotic importance. It is caused by B.anthracis, a gram positive spore which produces a toxin. Infection occur when the spore enter the body through a cut, abrasion, or open spore. Spore can survive many years in the soil. The severity of the disease is due to production of endotoxin. The endotoxin has three components: Edema factor, protective antigen and lethal factor. It has been typically seen associated with 3 forms of infection generally in human: Cutaneous, gastrointestinal, and inhalational. Cutaneous anthrax is the most common. Early symptoms with other disease forms can be non specific and mistaken for less lethal condition. Antibiotics are the mostly use for its treatment. Prompt for the control and prevention of the emerging disease, the contagious disease anthrax there is used of anti anthrax serum vaccination.